The Velora Protocol is a groundbreaking 3-step in-office process that allows practitioners to create a next-generation biological filler using the patient's own blood. Unlike a standard PRP or PRF treatment, Velora produces a smooth, moldable, injectable gel — with a consistency comparable to traditional dermal filler — made entirely from autologous materials.

The protocol combines:

• Step 1 — Centrifugation: Blood is drawn into Velora vacutainer tubes and spun at 3,500 RPM for 8 minutes to concentrate PRP

• Step 2 — LED Photo-Activation: PRP-filled syringes are exposed to polychromatic light for 10 minutes, amplifying growth factor and cytokine release by up to 7x with sustained expression over 28 days

• Step 3 — Bio-Incubation: The activated PRP is placed in the patented Bio-Incubator, where precise heating and cooling cycles convert it into injectable PRF gel — smooth, bioavailable, and ready to inject

The result: a fully personalized, regenerative filler derived entirely from the patient's own biology. Zero additives. Zero foreign substance. Zero migration risk.

PRP (Platelet-Rich Plasma) A concentration of platelets in plasma — approximately 3–5x the baseline found in whole blood. PRP releases growth factors rapidly upon activation and is the input for the Velora protocol. Best for: facial rejuvenation, microneedling enhancement, and hair restoration (Biotin Kit).

PRF (Platelet-Rich Fibrin) Platelets and leukocytes embedded in a fibrin matrix, created through the bio-incubation process. Growth factors are released slowly over time via the fibrin scaffold — producing longer-lasting regenerative effects. The Velora Bio-Incubator converts PRP into injectable PRF gel.

The Velora system uses both — PRP goes in, PRF biofiller comes out. The centrifuge and kit you choose determine whether you're producing PRP for microneedling/hair treatment or PRF gel for biofiller injection.

Not all PRP protocols are equal. Most providers don't realize how much their tube type and spin method affect growth factor quality and patient safety.

What Velora does differently:

• Single spin — clinically proven to produce higher-quality PRP than double-spin methods, which can damage platelets and reduce growth factor yield

• ACD (Citric Acid) anticoagulant — releases more growth factors than Sodium Heparin, reduces injection burn, and is safe for patients on blood thinners

• Mildly leukocyte rich (~9%) — the right balance to stimulate tissue remodeling and phagocytosis without triggering hyper-inflammation

• Polyester gel separator — automatically pushes PRP, PPP, and growth factors above the separator for clean, consistent extraction with less error and fewer wasted kits

• No yellow-top tubes (contain clot activators that interfere with PRP purity)

• No PET plastic tubes (can leach chemicals into the PRP)

LED Photo-Activation vs. Calcium Chloride/Thrombin: LED activation is the preferred method for regulatory compliance and delivers enhanced, more consistent growth factor expression — without adding foreign substances to the patient's plasma.

Bio-incubation is the step that makes Velora a biofiller — not just a PRP treatment. The patented Rize Up Bio-Incubator applies precise heating and cooling cycles to the activated PRP. This process denatures and self-assembles human serum albumin (HSA) — the most abundant protein in blood — into a fibrillar gel matrix that is smooth, moldable, and injectable.

Why the Rize Up Bio-Incubator outperforms dry block heaters:

• Individual nylon-insulated ports — uniform heat transfer to every syringe simultaneously

• Ceramic heater (not aluminum block) — faster, more controlled heating and cooling without burning or icing platelets or stimulating bacterial colonization

• Patented, purpose-built design — engineered specifically for biofiller creation, not repurposed lab equipment

The consistency of your PRF gel depends directly on your incubator. This isn't a commodity device.

Yes. The Velora PRP collection tube system maintains 510(k) clearance from the FDA through the ProGen PRP Eclipse (Crown Aesthetics). All kits are individually sterile packaged and ready for use.

The Bio-Incubator is a patented device. All protocols use the patient's own autologous blood — no foreign biologics, no synthetic additives, and no off-label injectable substances.

All treatments must be performed by licensed medical professionals in compliance with applicable state scope of practice guidelines.